OFFERSAugust 2026

Lips + Toxin: 1 HA + 3 Botox areas · $560 USD|Kim K Package: Endolift + Morpheus 8 · $2,000 USD|Diamond Jaw Contour: 10 HA + 5 FREE · $3,550 USD|Korean Glow: 2 Sculptra + Juvelook + PDRN · $1,750 USD|Sofwave Full Face: Skin tightening · $1,250 USD|Endo-Tightening: Endolift + RF Microneedling · $1,850 USD|Hollywood Lift: Hydrafacial + Peel · $260 USD|Hydralaser: Botox + 6 PDO Threads · $800 USD|Cellulite Total Correction: 3 PLLA vials · $1,400 USD|Total Anti-Age: 3 HA syringes · $700 USD|Lips + Toxin: 1 HA + 3 Botox areas · $560 USD|Kim K Package: Endolift + Morpheus 8 · $2,000 USD|Diamond Jaw Contour: 10 HA + 5 FREE · $3,550 USD|Korean Glow: 2 Sculptra + Juvelook + PDRN · $1,750 USD|Sofwave Full Face: Skin tightening · $1,250 USD|Endo-Tightening: Endolift + RF Microneedling · $1,850 USD|Hollywood Lift: Hydrafacial + Peel · $260 USD|Hydralaser: Botox + 6 PDO Threads · $800 USD|Cellulite Total Correction: 3 PLLA vials · $1,400 USD|Total Anti-Age: 3 HA syringes · $700 USD

Professional Depigmentation by Mesoestetic

Cosmelan in Tijuana

The world's #1 professional depigmentation method. Treat melasma, dark spots, and uneven skin tone safely on all skin types.

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Cosmelan professional depigmentation treatment at Vive Med Spa Tijuana

What is Cosmelan?

Cosmelan is the world's leading professional depigmentation method, developed by Mesoestetic, the Spanish pharmaceutical laboratory headquartered in Barcelona. The method is specifically designed to treat melasma, chloasma, post-inflammatory hyperpigmentation, sun spots, and uneven skin tone. It works by inhibiting the tyrosinase enzyme, the key enzyme responsible for melanin production, reducing pigmentation at its source rather than simply exfoliating the surface.

At Vive Med Spa in Tijuana, our certified Cosmelan physicians perform the in-office mask (Cosmelan 1) and provide the complete home maintenance protocol (Cosmelan 2) to ensure safe, effective, and long-lasting results. The treatment is suitable for all skin phototypes (Fitzpatrick I to VI), including darker skin, and is one of the few depigmentation methods clinically proven for stubborn hormonal melasma. Visible improvement is typically seen within 1 to 2 weeks, with continued improvement over 3 to 6 months.

The Cosmelan Protocol

Cosmelan 1 (In-Office Mask)

Professional depigmenting mask applied by the physician. The first and most intensive step of the Cosmelan method. Stays on the skin for 8-12 hours depending on phototype.

Cosmelan 2 (Home Maintenance Cream)

Daily depigmenting cream for home use. Maintains the results of the in-office mask by continuing to inhibit tyrosinase. Used for 6 to 12 months.

Cosmelan Home Maintenance Pack

Complete home care kit with Cosmelan 2, hydra-vital factor K cream, melan recovery cream, and total sun protection SPF 50+. Essential for results.

Cosmelan Hydra-Vital Factor K

Intensive hydrating cream with vitamin K, aloe vera, and shea butter. Soothes the skin and restores the barrier during the post-mask recovery phase.

Melan Recovery Cream

Post-treatment recovery cream that calms, hydrates, and accelerates the skin's recovery after the Cosmelan mask. Reduces redness and tightness.

Mesoprotech Total Sun Protection SPF 50+

High-protection tinted sunscreen specifically formulated to be used during and after the Cosmelan treatment. Prevents new dark spots and protects the skin from UV-induced melanin.

Cosmelan depigmentation results at Vive Med Spa Tijuana

Ready for Cosmelan?

Book a consultation with our certified Cosmelan physicians and start your journey to clear, even-toned skin.

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Benefits of Cosmelan

World's #1 Depigmentation Method

Used in more than 90 countries with millions of satisfied patients

Effective on Stubborn Melasma

Targets hormonal and resistant pigmentation that peels cannot resolve

Safe for All Skin Types

Clinically tested on Fitzpatrick I to VI phototypes

Dual In-Office + Home Protocol

Intensive mask + maintenance cream for long-lasting results

Visible Results in 1-2 Weeks

Significant improvement in skin tone after the first week

CE, FDA-Cleared, COFEPRIS

Compliant with the strictest European and Mexican regulations

Vive Med Spa - certified Cosmelan provider in Tijuana

Certified Mesoestetic Provider

Why Get Cosmelan at Vive Med Spa?

We are certified Cosmelan providers. The treatment is performed exclusively by our board-certified physicians who have completed the official Mesoestetic training program. The complete protocol — including the in-office mask, the maintenance cream, and all post-care products — is included. Inquire via WhatsApp for details. Our physicians will guide you through every step of the 6-12 month journey.

Certified Mesoestetic Cosmelan providers
Board-certified physicians with specialized training
Complete protocol included (mask + home kit)
Personalized follow-up for 6-12 months
Combinable with Glutanex and IPL for enhanced results

Frequently Asked Questions About Cosmelan

What is Cosmelan and what is it used for?

Cosmelan is the world's leading professional depigmentation method developed by Mesoestetic, the Spanish pharmaceutical laboratory. It is specifically formulated to treat melasma, chloasma, post-inflammatory hyperpigmentation, sun spots, and uneven skin tone. The treatment combines an in-office mask (Cosmelan 1) with a complete home maintenance protocol (Cosmelan 2) to reduce melanin production at its source and reveal a brighter, more even complexion.

How does the Cosmelan treatment work?

The Cosmelan method works by inhibiting the tyrosinase enzyme, which is responsible for melanin synthesis in the skin. The in-office mask is applied by a trained physician and remains on the skin for 8 to 12 hours, depending on skin type. After removal, patients follow a structured home-care protocol with Cosmelan 2 maintenance cream, sunscreen, and hydrating products for 6 to 12 months to consolidate and prolong the results.

What is the difference between Cosmelan and chemical peels?

Unlike chemical peels, which work by removing the top layers of the skin through controlled exfoliation, Cosmelan works at the cellular level by inhibiting the enzymatic processes that produce melanin. This makes it safer for darker skin types (Fitzpatrick III-V) and more effective for stubborn hormonal melasma that often recurs with peels. Cosmelan also has less downtime than medium-depth peels.

Is Cosmelan safe for all skin types?

Yes. Cosmelan is one of the few professional depigmentation treatments clinically tested and proven safe for all skin phototypes, including darker skin (Fitzpatrick IV, V, and VI). The protocol is customized by our physicians based on your skin type, melasma depth, and lifestyle. Strict sun avoidance and daily SPF 50+ sunscreen are mandatory during the entire treatment.

Where can I get Cosmelan treatment in Tijuana?

At Vive Med Spa, we are certified Cosmelan providers. The treatment is performed by our board-certified physicians at our clinic located at Av. Diego Rivera 2351, Zona Urbana Río, Tijuana, BC, Mexico. We serve patients from Tijuana, San Diego, Chula Vista, and all of Baja California. The complete Cosmelan protocol (in-office mask + home maintenance kit) is included — inquire via WhatsApp for details.